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Optical mapping and more recent genome mapping applied sciences according to nicking enzymes offer low solution yet long-range genomic details. The optical mapping strategy has been effectively used for assessing the standard of genome assemblies and for detecting large-scale structural editions and rearrangements that can not be detected utilizing present paired finish sequencing protocols. the following, we assessment numerous algorithms and techniques for development consensus optical maps and aligning restrict styles to a reference map, in addition to tools for utilizing optical maps with series assemblies.
Medical Content-Based Retrieval for Clinical Decision Support: Second MICCAI International Workshop, MCBR-CDS 2011, Toronto, Canada, September 22, ... Papers (Lecture Notes in Computer Science) review