Publisher: S. Karger; 1 edition (October 15, 2003)
Format: PDF / Kindle / ePub
Size: 9.8 MB
Downloadable formats: PDF
Pheochromocytomas are infrequent, in most cases benign tumors of the adrenal medulla whose signs are brought on by a tumor-induced secretion of catecholamines. This e-book offers an summary of present wisdom at the medical scenario, analysis and remedy of the sickness in addition to an intensive dialogue of novel facets within the molecular foundation of this sickness resembling the popularity of latest instruments in molecular biology. The endocrine analysis relies on distinctive wisdom of tumor metabolism of catecholamines and their metabolites and at the present time includes laboratory equipment with a excessive sensitivity and specificity. As nearly one area of those tumors come up within the context of a familial sickness, reminiscent of a number of endocrine neoplasia style 2, von Hippel-Lindau syndrome, neurofibromatosis kind 1 or familial paragangliomas, the genetic prognosis is changing into more and more appropriate. both necessary are imaging equipment corresponding to 123I-MIBG scintigraphy or octreotide scintigraphy, which are hired as a complementary technique in e.g. malignant tumors. The surgical remedy is obviously in line with the character of the affliction; in sporadic unilateral in addition to familial bilateral pheochromocytoma a lateral endoscopic method is selected. The therapy of malignant pheochromocytoma is especially in accordance with using nuclear clinical concepts and chosen chemotherapeutic ways. This publication is vital interpreting for clinicians and scientists within the fields of endocrinology in addition to oncology, surgical procedure and nuclear medication.